Effect of inoculation of bursa cells on the splenic lymphoid tissue of bursectomized and x-irradiated chickens.
نویسنده
چکیده
HOSHI, H. Effect of Inoculation of Bursa Cells on the Splenic Lymphoid Tissue of Bursectomized and X-irradiated Chickens. Tohoku J. exp. Med., 1972, 108 (2), 113-121 Bursectomized and X-irradiated chickens were given intraperitoneal inoculation of live bursa cells in an attempt to restore the periellipsoidal lymphoid cells in their spleens. An injection of viable cells prepared from autologous bursae into neonatally bursectomized and X-irradiated chickens produced no recognizable restoration of the bursa-dependent lymphoid elements, i.e., peri ellipsoidal lymphoid cells, germinal center cells and plasma cells. A slight res torative effect was found by inoculations on the 8th and 9th days of a large number of homologous bursa cells, which were obtained from newly hatched or 4-week -old chickens. In the chickens which were bursectomized, X-irradiated and given their own unirradiated bursa cells at around 2 weeks of age, all the bursa-dependent elements including the periellipsoidal lymphoid cells were found considerably restored. The result shown by the 2-week-old chickens was thought to provide a circumstantial support for the concept that the periellipsoidal lymphoid cells may be one of the cell lineages stemming from the bursal lymphoid cells. lymphoid tissue; spleen; bursa of Fabricius; chick
منابع مشابه
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ورودعنوان ژورنال:
- The Tohoku journal of experimental medicine
دوره 108 2 شماره
صفحات -
تاریخ انتشار 1972